Renagel (Sevelamer) 800mg

Sevelamer, Renvela/Renagel
Description: Phosphate Binder

CSA NA – FDA Approved – REMS (N) – Can Ship

Sevelamer, Renvela/Renagel binds phosphate within the intestinal tract, limiting absorption and decreasing serum phosphate concentrations without altering calcium, aluminum, or bicarbonate concentrations.

Control of serum phosphorous

Before starting Sevelamer, Renvela/Renagel make sure your physician is aware of any allergies or medications you currently take, if you have a bowel obstruction, an active mucosal injury, hypophosphatemia, other gastrointestinal disease, are pregnant, or breastfeeding. Sevelamer, Renvela/Renagel use has been associated with rare but serious adverse events such as bowel obstruction, GI ulcers, colitis, necrosis, perforation, dysphagia and esophageal tablet retention.

Control of serum phosphorous: Oral: 800 to 1,600 mg 3 times daily with meals; the initial dose may be based on serum phosphorous levels; maximum dose studied was equivalent to 13 g/day sevelamer hydrochloride or 14 g/day sevelamer carbonate.

Note: The dosing of sevelamer carbonate and sevelamer hydrochloride are similar; when switching from one product to another, the same dose (on a mg per mg basis) should be utilized.

How to Take: Administer with meals.  May prepare an oral suspension in water using the directed amount of water appropriate for the packet size or may premix the entire content of the packet with a small amount of food or beverage (do not heat or add to heated foods or liquids). Preparations should be consumed immediately or within 30 minutes. Oral suspension in water may need to be resuspended immediately before drinking. Swallow tablets whole; do not crush, chew, or break.  May cause reductions in vitamin D, E, K, or folic acid absorption so consider vitamin supplementation.

You Need to Avoid:  Significant drug interactions exist, requiring dose/frequency adjustment or avoidance so avoid starting any new medications without consulting prescriber.

Metabolic acidosis, diarrhea, dyspepsia, nausea, vomiting, abdominal pain, constipation, flatulence, peritonitis

Note this is not a complete list of side effects, only the most common

1. What do I do if side effects are intolerable?
   If side effects are causing a lot of distress speak to your physician as soon as possible to discuss options.