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Progesterone 100mg

Description Of Product


“ALERT: US Boxed Warning

Cardiovascular disorders (capsule):

Estrogens plus progestin therapy should not be used for the prevention of cardiovascular disorders. The Women’s Health Initiative (WHI) estrogen plus progestin substudy reported increased risks of myocardial infarction (MI), stroke, pulmonary embolism (PE), and deep vein thrombosis (DVT) in postmenopausal women (50 to 79 years of age) during 5.6 years of treatment with daily oral conjugated estrogens 0.625 mg combined with medroxyprogesterone 2.5 mg relative to placebo.

Probable dementia (capsule):

Estrogens plus progestin therapy should not be used for the prevention of dementia. The Women’s Health Initiative Memory Study (WHIMS) estrogen plus progestin ancillary study of the WHI reported an increased risk of developing probable dementia in postmenopausal women 65 years and older during 4 years of treatment with daily conjugated estrogens 0.625 mg combined with medroxyprogesterone 2.5 mg, relative to placebo. It is unknown whether this finding applies to younger postmenopausal women.

Breast cancer (capsule):

The WHI estrogen plus progestin substudy also demonstrated an increased risk of invasive breast cancer.

Risks versus benefits (capsule):

In the absence of comparable data, assume these risks to be similar for other doses of conjugated estrogens and medroxyprogesterone and other combinations and dosage forms of estrogens and progestins. Prescribe progestins with estrogens at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.”

CSA NA – FDA Approved – REMS (N) – Can Ship

How Does It Work

Progesterone is a steroid hormone that plays a regulatory role in the female reproductive system by allowing the endometrium to transition from a proliferative to the secretory stage, facilitates blastocyst nesting and is essential to the maintenance of pregnancy.  Progesterone also plays an important role in several tissues not belonging to the reproductive system, such as the mammary gland in preparation for breastfeeding, the cardiovascular system, central nervous system, and bones.

Indications For Use

Officially indicated for the prevention of endometrial hyperplasia, treatment of secondary amenorrhea or abnormal uterine bleeding, and for postmenopausal women who are receiving conjugated estrogens.


Use with caution in postmenopausal women using conjugated estrogens in combination with medroxyprogesterone acetate

Use with caution in patients who perform tasks that require mental alertness

Use with caution in patients who may have asthma, cardiac impairment, epilepsy, migraines, and diabetes due to a higher risk of fluid retention

Use with caution in patients who may have depression

Do not use in cases of hepatic and/or renal impairment

Do not use during pregnancy

Usual Dosing

Oral: Take 400mg once daily at bedtime for 10 days.

Endometrial hyperplasia, prevention
Oral: Take 200mg once daily at bedtime for 12 days sequentially per 28-day cycle.

Pharmacist Tips On Using

How Do You Take the Progesterone/Prometrium: You can take with food to increase oral absorption of Prometrium/Progesterone.   Take the medication exactly as prescribed by your doctor at the same time each day.  If you miss a dose, make sure to take it as soon as possible.  However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Contact Your Doctor if You Ever Experience:  If you experience a sudden, intense, severe headache or chest pain; sudden loss of coordination; sudden loss of vision or speech disturbances; chest or calf pain; weakness in the extremities; sudden shortness of breath of pain with breathing (may indicate thromboembolic disorder); persistent or recurrent vaginal bleeding (may indicate endometrial cancer); edema; abdominal pain or jaundice (may indicate hepatitis or gallbladder disease).

Side Effects



Central Nervous System: Headache (16% to 31%), dizziness (15% to 24%), depression (19%)

Endocrine and Metabolic: Breast tenderness (27%), mastalgia (6% to 16%)

Gastrointestinal: Abdominal pain (20%), bloating (12%)

Genitourinary: Urinary tract abnormality (11%)

Infection: Viral infection (12%)

Neuromuscular and Skeletal: Musculoskeletal pain (12%)

Disclaimer: All information contained in and provided by UBACARE Your Intelligent Health Company is provided for educational purposes only. This information should not be used for diagnosis or treatment of any health problem or disease. This information is not intended to replace clinical judgement or guide individual patient care in any manner.

The User is hereby notified that the information contained herein may not meet the user’s needs. The User is advised that, although the information is derived from medical research and literature, we cannot guarantee either its correctness, comprehensiveness or currency.

UBACARE Your Intelligent Health Company nor any of its affiliated parties shall be liable for any damage resulting in whole or part from any User’s use of or reliance upon the information contained within.


All orders received prior to 3:00pm PST on business days will ship the following day; peak season and holiday shipping days may require an additional 24 hours. UBACARE Pharmacy will make every effort to ship each order as quickly as possible. Orders received over the weekend will ship the following Monday as our shipping department is closed Saturday and Sunday.

We offer shipping via Canada Post within Canada.
We offer shipping via USPS and UPS within the continental United States and worldwide. Expedited shipping options are available at checkout if you want to receive your order sooner.

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UBACARE is committed to providing transparency for all its products sold online. We will share with you details such as production country, supplier names and approval status so it is easier for our customers to make more informed choices when shopping with us.

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UBACARE stands behind the quality of our exclusive line products by offering a 100 percent money-back guarantee to ensure customer satisfaction. To ensure the best quality, all UBACARE products are held to the strict guidelines to achieve both FDA and Health Canada Approval. UBACARE recognizes the outside agencies such as the FDA cannot control what manufacturers in other countries do and that no amount of FDA inspection can ensure a reliable supply of vital medical products. As a result, UBACARE has elected dispense primarily Canadian made generics drugs to minimize risk of contaminated products.

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Our team of pharmacists and technicians will work with you and your doctor to find therapeutic alternatives and other options to help you save.

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Providing You Quality
with Unmatched Affordability

We only sell brand and generic drugs that we can confidently assure are safe and effective.
UBACARE has taken the initiative on selling ONLY generics drug companies that source their API and FDF from North American and European companies who have the proven capabilities of meeting high-quality standards.


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