Flutamide 250mg

Antineoplastic Agent, Antiandrogen

“Alert: Black Box Warning

Hepatic Injury

There have been postmarketing reports of hospitalization and rarely death due to liver failure in patients taking flutamide. Evidence of hepatic injury included elevated serum transaminase levels, jaundice, hepatic encephalopathy and death related to acute hepatic failure. The hepatic injury was reversible after discontinuation of therapy in some patients.”

CSA NA – FDA Approved – REMS (N) – Can Ship 

Flutamide is a nonsteroidal antiandrogen that inhibits androgen uptake and/or inhibits binding of androgen in target tissues.

Prostate Cancer

Before starting Flutamide make sure your physician is aware of any allergies or medications you currently take.  Flutamide like other antiandrogens can cause gynecomastia and hepatic failure.

Oral: 250mg 3 times daily.

How to Take: Can be taken with or without food in 3 divided doses.

Hot flashes, galactorrhea, decreased libido, diarrhea, vomiting, impotence, cystitis, breast tenderness, rectal hemorrhage, tumor flare, elevated liver enzymes, edema, hypertension, anxiety, confusion, depression, dizziness, headache, insomnia, nervousness, skin rash, gynecomastia, nausea, proctitis, dyspepsia, increased appetite, hematuria, hematologic disturbances (i.e. anemia, leukopenia, thrombocytopenia), Herpes Zoster, weakness.

Note this is not a complete list of side effects for Flutamide only common ones.

1. Why would my physician prescribe a medication with such serious side effects?
   Your physician takes the most recent clinical guidelines to make evidence-based decisions on what medication is appropriate in which situations.  Your current medications, your allergies, age, cost of medication, comorbid conditions and many other factors will further complicate or limit which medications are appropriate.  This medication is used for certain forms of cancer and your physician has determined the benefits outweigh the risks.   Furthermore, they will be monitoring your bloodwork and symptoms closely to avoid many of the serious side effects and will keep you on the lowest effective dosage for the shortest amount of time possible.