Raloxifene 60mg

Selective estrogen receptor modulator (SERM)

“ALERT: US Boxed Warning

Increased risk of VTE:

          Increased risk of deep vein thrombosis and pulmonary embolism have been reported with raloxifene. Women with active or history of VTE should not take raloxifene.

 Cardiovascular disease:

          Increased risk of death due to stroke occurred in a trial in postmenopausal women with documented coronary heart disease or increased risk for major coronary events. Consider the risk-benefit balance in women at risk for stroke.”

CSA NA – FDA Approved – REMS (N) – Can Ship

Raloxifene, Evista is a selective estrogen receptor modulator (SERM) that has a complex mechanism of action where it has estrogen like activity in the bones to prevent osteoporosis, but blocks estrogen activity in the breast and uterine tissue.

Raloxifene, Evista is officially indicated for treatment of osteoporosis in post-menopausal females while also reducing the risk of some forms of invasive breast cancer.

Before starting Raloxifene, Evista make sure your physician is aware of any allergies or medications you currently take, if you have kidney disease, liver disease, high triglycerides, unexplained uterine bleeding, or have a history of breast cancer.

60mg once daily without regard to meals

How Do You Take Raloxifene, Evista:  Raloxifene, Evista can be taken with or without food.  Take the medication exactly as prescribed by your doctor at the same time each day.  If you miss a dose, make sure to take it as soon as possible.  However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.  It is also recommended that osteoporosis patients supplement with calcium and vitamin D if dietary intake is below recommended values.

Do Not Use Raloxifene, Evista: If you have a known hypersensitivity to Raloxifene, Evista or any component of the formulation, it has not been studied in males or premenopausal women so it should not be used on either patient group.

>10%:

Cardiovascular: Peripheral edema (3% to 14%)

Endocrine & metabolic: Hot flash (8% to 29%)

Infection: Infection (11%)

Neuromuscular & skeletal: Arthralgia (11% to 16%), leg cramps (≤12%), muscle spasm (≤12%)

Respiratory: Flu-like symptoms (14% to 15%)