Name: Prograf (Tacrolimus) 1mg
SKU: 3980
Price: 334.99 USD
Availability: InStock

100 cap

Prograf (Tacrolimus) 1mg

$334.99

Brand Manufacturer: ASTELLAS PHARMA CANADA

Categories: Inflammation and Immune System, Skin

Additional information

Additional information

100 cap

Free shipping on orders $500 and over.

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not an agent, venture or employed by UBACARE.

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Description Of Product

Calcineurin Inhibitor

“ALERT: US Boxed Warning

Malignancies and serious infection:

Increased risk for developing serious infections and malignancies with tacrolimus or other immunosuppressants that may lead to hospitalization or death.

Mortality in liver transplantation (Astagraf XL):

Increased mortality in female transplant patients with Astagraf XL. Astagraf XL is not approved for use in liver transplantation.”

CSA NA – FDA Approved – REMS (N) – Can Ship

How Does It Work

Tacrolimus suppresses cellular immunity (inhibits T-lymphocyte activation), by binding to an intracellular protein, FKBP-12, and complexes with calcineurin dependent proteins to inhibit calcineurin phosphatase activity. Inhibition of calcineurin also is important in maintaining neuronal and synaptic integrity and homeostasis for peripheral nerve regeneration.

Indications For Use

Officially indicated for organ rejection prophylaxis. It is also prescribed off-label for use in Crohn disease (perianal/fistulizing disease), graft-versus host disease (prevention/treatment), immunosuppression (maintenance) after lung transplant, intestinal transplant, myasthenia gravis, rheumatoid arthritis (refractory), and peripheral nerve regeneration.

Precautions

Do not use in patients with a known hypersensitivity to tacrolimus.

Do not use in patients with congenital long QT syndrome

Use with caution in patient with heart failure, brady arrhythmia, taking antiarrhythmic mediations or other drugs that can lead to QT prolongation

Immunosuppressant agents including tacrolimus can increase the risk of infection leading to hospitalization or death

Immunosuppressive agents including tacrolimus may be associated with the development of malignancies that can lead to hospitalization or death

Usual Dosing

Immunosuppressants such as tacrolimus have a wide range of dosing options. For a comprehensive listing, please check an official drug monograph.

Side Effects

Immunosuppressants such as tacrolimus have an extensive side effect profile. For a comprehensive listing, please check an official drug monograph.

Disclaimer: All information contained in and provided by UBACARE Your Intelligent Health Company is provided for educational purposes only. This information should not be used for diagnosis or treatment of any health problem or disease. This information is not intended to replace clinical judgement or guide individual patient care in any manner.

The User is hereby notified that the information contained herein may not meet the user’s needs. The User is advised that, although the information is derived from medical research and literature, we cannot guarantee either its correctness, comprehensiveness or currency.

UBACARE Your Intelligent Health Company nor any of its affiliated parties shall be liable for any damage resulting in whole or part from any User’s use of or reliance upon the information contained within.

SHIPPING

All orders received prior to 3:00pm PST on business days will ship the following day; peak season and holiday shipping days may require an additional 24 hours. UBACARE Pharmacy will make every effort to ship each order as quickly as possible. Orders received over the weekend will ship the following Monday as our shipping department is closed Saturday and Sunday.

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