Gonal-F (Follitropin Alfa) Pen Injection 300iu

Follitropin Alfa, Gonal-f
Description: Gonadotropin; Ovulation Stimulator

CSA NA – FDA Approved – REMS (N) – Can Ship

Follitropin Alfa, Gonal-f is a human FSH preparation of recombinant DNA origin. Follitropins stimulate ovarian follicular growth in women who do not have primary ovarian failure and stimulate spermatogenesis in men with hypogonadotrophic hypogonadism.

Multifollicular development during Assisted Reproductive Technology (ART); Ovulation induction; Spermatogenesis induction (Gonal-f only)

Before starting Follitropin Alfa, Gonal-f make sure your physician is aware of any allergies or medications you currently take, if you have primal gonadal failure (high FSH), ingracranial lesions, uncontrolled nongonadal endocrinopathies, a hormone dependant tumor, undiagnosed abnormal vaginal bleeding, ovarian cysts, ovarian enlargement, are pregnant, or breastfeeding. Follitropin Alfa, Gonal-f use has been associated with rare but serious adverse events such as increased risk of spontaneous abortion, ectopic pregnancy, hypersensitivity reactions, ovarian enlargement, ovarian hyperstimulation syndrome, ovarian torsion, ovarian neoplasms, pulmonary effects, and thromboembolic events.

Ovulation induction: Females: SubQ: Start with 75 units daily and titrate as required to a maximum doseof 300 units daily. Treatment should be continued until follicular growth and/or serum estradiol levels indicate an adequate ovarian response.
Multifollicular development during ART: Females: SubQ: Initiate therapy with follitropin alfa in the early follicular phase (cycle day 2 or day 3) at a dose of 150 units daily, until sufficient follicular development is attained.
Spermatogenesis induction: Males: Gonal-f: SubQ: Initiate Gonal-f at 150 units 3 times weekly and adjust up to 300 units 3 times weekly with hCG 3 times weekly continuing with the lowest dose needed to induce spermatogenesis.

How to Take: Administer Subcutaneously. Contents of multidose vials should be administered using the calibrated syringes provided by the manufacturer.  Store powder refrigerated or at room temperature of 2°C to 25°C (36°F to 77°F). Protect from light. Dose should be individualized. Use the lowest dose consistent with the expectation of good results. Over the course of treatment, doses may vary depending on individual patient response.

You Need to Avoid:  Significant drug interactions exist, requiring dose/frequency adjustment or avoidance so avoid starting any new medications without consulting prescriber.  Do not shake solution; allow any bubbles to settle prior to administration.  Do not allow product to freeze.

Varicocele, headache, acne vulgaris (males), ovarian cyst, abdominal pain, nausea, enlargement of abdomen, mastalgia (males), injection site reaction, upper respiratory tract infection

Note this is not a complete list of side effects, only the most common

1. What do I do if side effects are intolerable?
   If side effects are causing a lot of distress speak to your physician as soon as possible to discuss options.