Glyburide 5mg

Antidiabetic Agent; Sulfonylurea

CSA NA – FDA Approved – REMS (N) – Can Ship

Glyburide/Glibenclamide, Glynase/Diabeta stimulates the release on insulin from insulin producing beta cells in pancreas, reduces glucose release from the liver and increases peripheral insulin sensitivity

Glyburide/Glibenclamide, Glynase/Diabeta is indicated for Diabetes Mellitus Type 2

Before starting Glyburide/Glibenclamide, Glynase/Diabeta make sure your physician is aware of any allergies (sulfa), medications you currently take, if you have kidney disease,  have had bariatric surgery, glucose-6-phosphate dehydrogenase deficiency, are in a high stress state (had surgery, trauma, infection, fever), are pregnant or breastfeeding

1.25-20mg daily divided into one or two daily doses 

Note micronized tablets such as Glynase Prestab in the US are not equivalent to standard tablets.
These are dosed 0.75-12mg daily divided into one or two daily dosages

How to Take: Follow instructions provided by physician/pharmacy label, take consistently at same times each day with a meal unless otherwise directed, store at room temperature. Dosages above 10mg/day (>6mg/day micronized) generally should be divided for better blood sugar control.

You Need to Avoid: If you reduce your caloric intake or are fasting then this medication may need to be reduced or held to avoid hypoglycemia.  Alcohol can rarely cause a disulfiram reaction with this medication which is akin to an immediate severe “hangover” with consumption of even a small amount of alcohol.  If this occurs, then avoid alcohol or speak to physician about your options.

Epigastric fullness, heartburn, nausea, hypersensitivity reaction (rash, itch, hives)

Note this is not a complete list of side effects, only common ones

1. What is hypoglycemia?
   Hypoglycemia is a condition of low blood sugar (>3.9mmol/L-Canada; 70mg/dL-US) which is considered a medical emergency whereas hyperglycemia is a slow progressive condition.  It generally occurs with irregularities in diet, exercise, and medications in diabetic patients.  It is preferably treated with simple sugars such as dextrose; regular table sugar can work but is slower acting as it needs to be digested and if blood sugar is extremely low this delay can be a problem.  Hypoglycemia has a large host of progressive symptoms from hunger, headache, nausea, sweating, palpitations, mood swings, irritability to seizure, coma and in severe cases, death.