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Fluticasone/Salmeterol 100mcg/50mcg

Description Of Product

Fluticasone+Salmeterol, Advair/AirDuo/Wixela
Description: Inhaled corticosteroid; Long acting Beta 2 Adrenergic Agonist

CSA NA – FDA Approved – REMS (N) – Can Ship

How Does It Work

Salmeterol relaxes the smooth muscle in the bronchioles via the beta2-adrenergic receptor. Fluticasone may reduce the formation, release, and activity of inflammatory mediators such as kinins, histamine and prostaglandins.  It reduces cell migration to the affected area and reverses the dilation and blood vessel permeability result in decreased access of cells to the site.

Indications For Use

Fluticasone+Salmeterol, Advair/AirDuo/Wixela is indicated for asthma and chronic obstructive pulmonary disease (may also be used for conditions not listed)


Before starting Fluticasone+Salmeterol, Advair/AirDuo/Wixela make sure your physician is aware of any allergies (lactose- note that this is for true allergy, not dietary lactose intolerance which is from a lack of lactase), medications you currently take, if you have cardiovascular disease, diabetes, liver disease, have hypokalemia, are pregnant, or breastfeeding

Usual Dosing

Generally dosed twice daily, with the salmeterol component determining maximum dosage (50mcg twice a day) regardless of the inhaler design.  The strength of the steroid component is determined by severity of symptoms and patient response.  If the steroid component must be increased, then another formulation with more steroid may be used or an additional single entity steroid inhaler may be added.

Pharmacist Tips On Using

How to Take Fluticasone+Salmeterol, Advair/AirDuo/Wixela: Follow instructions provided by physician/pharmacy label, take consistently at same times each day, store at room temperature.  Follow priming instructions for the product received and make sure the pharmacist teaches you proper use/care of the device as there are various styles of inhaler available containing this combination.   Rinse mouth with water and spit out after every use of medication to reduce risk of oral thrush.

You Need to Avoid: Do not exceed recommended dosages to avoid adverse reactions

Side Effects

Headache, upper respiratory tract infection, pneumonia, pharyngitis

Note this is not a complete list of side effects, only the most common ones.

Frequently Asked Questions

  1. My symptoms have not improved with use of this medication, what do I do?
    Seek medical attention, especially if an asthma attack or COPD exacerbation.
  2. Why is my heart racing/ am I stimulated after using this medication?
    Salmeterol works on specific adrenaline receptors however it sometimes will activate other adrenaline receptors that results in increased heart rate/ mental stimulation.  It generally does not affect heart rate too much but can occur.
  3. Why does one brand of inhaler feel differently than another?
    Different brands of metered dose inhalers may use different propelling agents and dry powder inhalers have such a small amount of powder dispensed you likely will not feel it.

Disclaimer: All information contained in and provided by UBACARE Your Intelligent Health Company is provided for educational purposes only. This information should not be used for diagnosis or treatment of any health problem or disease. This information is not intended to replace clinical judgement or guide individual patient care in any manner.

The User is hereby notified that the information contained herein may not meet the user’s needs. The User is advised that, although the information is derived from medical research and literature, we cannot guarantee either its correctness, comprehensiveness or currency.

UBACARE Your Intelligent Health Company nor any of its affiliated parties shall be liable for any damage resulting in whole or part from any User’s use of or reliance upon the information contained within.


All orders received prior to 3:00pm PST on business days will ship the following day; peak season and holiday shipping days may require an additional 24 hours. UBACARE Pharmacy will make every effort to ship each order as quickly as possible. Orders received over the weekend will ship the following Monday as our shipping department is closed Saturday and Sunday.

We offer shipping via Canada Post within Canada.
We offer shipping via USPS and UPS within the continental United States and worldwide. Expedited shipping options are available at checkout if you want to receive your order sooner.

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UBACARE stands behind the quality of our exclusive line products by offering a 100 percent money-back guarantee to ensure customer satisfaction. To ensure the best quality, all UBACARE products are held to the strict guidelines to achieve both FDA and Health Canada Approval. UBACARE recognizes the outside agencies such as the FDA cannot control what manufacturers in other countries do and that no amount of FDA inspection can ensure a reliable supply of vital medical products. As a result, UBACARE has elected dispense primarily Canadian made generics drugs to minimize risk of contaminated products.

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Our team of pharmacists and technicians will work with you and your doctor to find therapeutic alternatives and other options to help you save.

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with Unmatched Affordability

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UBACARE has taken the initiative on selling ONLY generics drug companies that source their API and FDF from North American and European companies who have the proven capabilities of meeting high-quality standards.


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