Acitretin 10mg

Retinoid-Like Compound

“Alert: Black Box Warning

Acetretin, Soritane has been linked to cause fetal abnormalities.  Acetretin, Soritane should not be used by females who are pregnant, or who intend to become pregnant during therapy or at any time for at least 3 years following discontinuation of therapy.  Acitretin, Soritane should be considered only for women with severe psoriasis unresponsive to other therapies or whose clinical condition contraindicates the use of other treatments.  Females of reproductive potential must not be given a prescription for acitretin until pregnancy is excluded. “

CSA NA – FDA Approved – REMS (N) – Can Ship

Acitretin, Soriatane works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.

Severe Psoriasis in adults

Before starting Acitretin, Soriatane make sure your physician is aware of any allergies or medications you currently take. Firstly, pregnancy needs to be excluded prior to starting treatment with Acitretin, Soriatane.  Acetretin, Soriatane use has been shown to cause capillary leak syndrome, depression, exfoliative dermatitis, hepatotoxicity, abnormal lipid levels, tinnitus, photosensitivity, pseudotumor cerebri, skeletal abnormalities and visual disturbances.  Consider therapy discontinuation and further evaluation if clinically indicated.

Oral: 25mg to 50mg daily.

How to Take:  Take with the main meal of the day.

Hyperesthesia, paresthesia, rigors, cheilitis, alopecia, exfoliation of skin, xeroderma, nail disease, pruritis, skin rash, skin atrophy, hypertriglyceridemia, decreased HDL cholesterol, hypercholesterolemia, elevated liver enzymes, electrolyte disturbances, hematuria, leukocyturia, reticulocytosis, joint pain, spinal hyperostosis, dry eyes, rhinitis, epistaxis.

Note this is not a complete list of side effects for Acitretin, Soriatane only common ones

1. Why would my physician prescribe a medication with such serious side effects?
   Your physician takes the most recent clinical guidelines to make evidence-based decisions on what medication is appropriate in which situations.  Your current medications, your allergies, age, cost of medication, comorbid conditions and many other factors will further complicate or limit which medications are appropriate.  This medication is used for severe psoriasis in adults that does not respond to medications with fewer side effects.  Furthermore, they will be monitoring your bloodwork and symptoms closely to avoid many of the serious side effects and will keep you on the lowest effective dosage for the shortest amount of time possible.